Sugar acids and derivatives
![Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000286978.png-250.jpg)
Medchemexpress LLC 7-chloro-3-(2,4-dimethoxyphenyl)-5-methyl-thiazolo[4,5-d]pyrimidine-2-thione | 2459916-56-2 | 98.5% | 353.85 g/mol | C14H12ClN3O2S2 | 10 MG
CDK1/Cyc B-IN-1 is a small-molecule inhibitor selective for the CDK1-cyclin B kinase complex. It inhibits CDK1-cyclin B activity (reported IC50 ≈97 nM) and induces G2/M cell-cycle arrest and apoptosis in cancer cell lines. The compound is supplied as a solid with high purity and is used in biochemical and cellular studies of cell-cycle regulation.
- Selective CDK1-cyclin B inhibitor with reported IC50 ≈97 nM.
- Induces G2/M cell-cycle arrest and apoptosis in cell lines.
- Suitable for biochemical kinase assays and cell-based studies.
- High supplied purity for reproducible results.
- Soluble in DMSO at 100 mg/mL; use newly opened DMSO.
- Stable as a powder under recommended cold storage conditions.
Medchemexpress LLC (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide | 1147883-03-1 | 99.3% | 265.30 g/mol | C14H19NO4 | 25MG
EPI-589 is a redox-active small-molecule neuroprotective compound used in research on oxidative stress and neurodegenerative disorders. Supplied as a light yellow powder, it is formulated for both in vitro and in vivo experimentation and is readily soluble in DMSO with recommended vehicle formulations for animal dosing. The compound is characterized and shelf-stable under appropriate storage conditions.
- High purity: 99.3%.
- Chemical formula: C14H19NO4.
- Molecular weight: 265.30 g/mol.
- Form: solid powder, light yellow to yellow.
- In vitro solubility: DMSO 100 mg/mL.
- Recommended in vivo vehicles and clear solution ≥ 2.5 mg/mL.
- Storage: powder at -20°C (long term) or 4°C (short term).
Medchemexpress LLC Protac α-synuclein degrader 5 | 2781922-42-5 | 100.0% | 767.78 g/mol | C39H41N7O10 | 10 MG
PROTAC α-synuclein degrader 5 is a small-molecule PROTAC designed to selectively target and promote degradation of α-synuclein aggregates in cellular models. Supplied as a high-purity solid for preclinical research, it shows dose-dependent activity in fibril-seeding assays and is formulated for in vitro and in vivo use.
- Selective degradation of α-synuclein aggregates (DC50 ≈ 7.5 μM, Dmax 89%).
- Demonstrated reduction of aggregates within 48 hours in PFF seeding cell models.
- High-purity solid suitable for biochemical and cellular assays.
- High solubility in DMSO for in vitro applications (≥100 mg/mL).
- Compatible with in vivo formulation protocols and frozen storage for stability.
![Apexbio Technology LLC vitamin D binding protein precursor (353-363) [Homo sapiens] 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000096705.png-250.jpg)
Apexbio Technology LLC vitamin D binding protein precursor (353-363) [Homo sapiens] 10mg
Vitamin D binding protein precursor 353-363 is a serum glycoprotein fragment derived from Homo sapiens It is associated with vitamin D binding protein (DBP) a plasma protein that binds vitamin D metabolites and actin monomers mediating transport in the bloodstream and regulation of extracellular actin levels DBP is present on surfaces of various immune cell types including B and T lymphocytes as well as placental cytotrophoblasts Based on these pharmacological properties vitamin D binding protein precursor 353-363 holds research potential in studies of vitamin D metabolism immune regulation and cytoskeletal interactions
Medchemexpress LLC JBI-589 | 2308504-22-3 | 99.8% | 481.56 g·mol⁻¹ | C29H28FN5O | 10 MG
JBI-589 is a non-covalent, isoform-selective inhibitor of peptidylarginine deiminase 4 (PAD4) with oral bioavailability, developed for preclinical cancer and immunology research. It reduces CXCR2 expression, blocks neutrophil chemotaxis, and has shown activity in reducing primary tumor growth and metastasis in experimental studies.
- Selective PAD4 inhibition with demonstrated activity in cellular assays.
- Orally bioavailable small molecule suitable for in vivo studies.
- High chemical purity for research use.
- Soluble in DMSO at high concentrations (requires sonication).
- Stable when stored under recommended powder and solvent conditions.
Apexbio Technology LLC HMP Linker 68858-21-9 100g
HMP Linker is an acid-sensitive linker used in solid-phase peptide synthesis (SPPS) It is designed to facilitate the covalent attachment of peptide carboxy-terminal residues to solid-phase resin supports and enables controlled cleavage of synthesized peptides under mildly acidic conditions thereby preserving the structural integrity of sensitive functional groups and peptide termini HMP Linker acts primarily by hydrolyzing upon acid catalysis which allows the intact release of peptides from resin supports Based on these properties HMP Linker holds research potential in peptide therapeutics synthesis and studies requiring mild peptide cleavage conditions
![eMolecules 383132-63-6 | 6-(Methylsulfonyl)-1h-indole-2-carboxylic acid | Combi-Blocks | MFCD02664464 | 239.250 | C10H9NO4S | 96.000 | CS(=O)(=O)c1ccc2cc([nH]c2c1)C(O)=O | 1g | 401039913](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502184941.JPG-250.jpg)
eMolecules 383132-63-6 | 6-(Methylsulfonyl)-1h-indole-2-carboxylic acid | Combi-Blocks | MFCD02664464 | 239.250 | C10H9NO4S | 96.000 | CS(=O)(=O)c1ccc2cc([nH]c2c1)C(O)=O | 1g | 401039913
6-(Methylsulfonyl)-1h-indole-2-carboxylic acid | Combi-Blocks | 383132-63-6 | MFCD02664464 | 239.250 | C10H9NO4S | 96.000 | CS(=O)(=O)c1ccc2cc([nH]c2c1)C(O)=O | 1g | 401039913
Sigma Aldrich Fine Chemicals Biosciences Polygalacturonic acid >=85% (titration), from oranges | 25990-10-7 | MFCD00131972 | 5G
Polygalacturonic acid >=85% (titration), from oranges | Purity: >=85% (titration) | 25990-10-7 | MFCD00131972 | 5G
Medchemexpress LLC Heparin calcium (MW 3600-5000) | 37270-89-6 | 3600-5000 Da | 100 MG
Heparin calcium (MW 3600-5000) is the calcium salt form of heparin, a polydisperse sulfated glycosaminoglycan anticoagulant supplied as a solid for research use. It acts by binding antithrombin III, accelerating inactivation of thrombin and other activated clotting factors to prevent fibrin formation. Supplied in low-molecular-weight fractions with an average molecular weight range of 3600-5000 Da.
- Anticoagulant action via antithrombin III binding.
- Low molecular weight range: 3600-5000 Da.
- Calcium salt supplied as a solid form.
- Intended for research use only, not for clinical use.
- Common pack size: 100 mg.
Sigma Aldrich Fine Chemicals Biosciences N-Acetylneuraminic acid from Escherichia coli, >=98% | 131-48-6 | MFCD00006620 | 100MG
N-Acetylneuraminic acid from Escherichia coli, >=98% | Purity: >=98% | Mol Wt: 309.27 | 131-48-6 | MFCD00006620 | 100MG
Sigma Aldrich Fine Chemicals Biosciences N-Acetylneuraminic acid synthetic, >=95% | 131-48-6 | MFCD00006620 | 100MG
N-Acetylneuraminic acid synthetic, >=95% | Purity: >=95% | Mol Wt: 309.27 | 131-48-6 | MFCD00006620 | 100MG
U.S. Pharmacopeia N-Acetylneuraminic acid | 131-48-6 | MFCD00006620 | 200 mg
N-Acetylneuraminic acid | Mol Wt: 345.30 | 131-48-6 | MFCD00006620 | 200 mg